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A biosensor-CMOS platform and integrated readout circuit in 0.18-μm CMOS technology for cancer biomarker detection
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Wed, Apr 26 2017
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Biosensors
ssat
CMOS
Abdulaziz Alhoshany, et al., " A biosensor-CMOS platform and integrated readout circuit in 0.18-μm CMOS technology for cancer biomarker detection". Sensors, 17(9), 2017, 1942. This paper presents a biosensor-CMOS platform for measuring the capacitive coupling of biorecognition elements. The biosensor is designed, fabricated, and tested for the detection and quantification of a protein that reveals the presence of early-stage cancer. For the first time, the spermidine/spermine N1 acetyltransferase (SSAT) enzyme has been screened and quantified on the surface of a capacitive sensor. The sensor